YDR270W

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Systematic name YDR270W
Gene name CCC2
Aliases
Feature type ORF, Verified
Coordinates Chr IV:1005675..1008689
Primary SGDID S000002678


Description of YDR270W: Cu(+2)-transporting P-type ATPase, required for export of copper from the cytosol into an extracytosolic compartment; has similarity to human proteins involved in Menkes and Wilsons diseases[1][2]




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References

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  1. Fu D, et al. (1995) Sequence, mapping and disruption of CCC2, a gene that cross-complements the Ca(2+)-sensitive phenotype of csg1 mutants and encodes a P-type ATPase belonging to the Cu(2+)-ATPase subfamily. Yeast 11(3):283-92 SGD PMID 7785328
  2. Yuan DS, et al. (1995) The Menkes/Wilson disease gene homologue in yeast provides copper to a ceruloplasmin-like oxidase required for iron uptake. Proc Natl Acad Sci U S A 92(7):2632-6 SGD PMID 7708696

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