YDR263C

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Systematic name YDR263C
Gene name DIN7
Aliases DIN3
Feature type ORF, Verified
Coordinates Chr IV:995534..994242
Primary SGDID S000002671


Description of YDR263C: Mitochondrial nuclease functioning in DNA repair and replication, modulates the stability of the mitochondrial genome, induced by exposure to mutagens, also induced during meiosis at a time nearly coincident with commitment to recombination[1][2][3][4]




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References

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  1. Fikus MU, et al. (2000) The product of the DNA damage-inducible gene of Saccharomyces cerevisiae, DIN7, specifically functions in mitochondria. Genetics 154(1):73-81 SGD PMID 10628970
  2. Koprowski P, et al. (2003) Enhanced expression of the DNA damage-inducible gene DIN7 results in increased mutagenesis of mitochondrial DNA in Saccharomyces cerevisiae. Mol Genet Genomics 269(5):632-9 SGD PMID 12827502
  3. Mieczkowski PA, et al. (1997) Characterization of a novel DNA damage-inducible gene of Saccharomyces cerevisiae, DIN7, which is a structural homolog of the RAD2 and RAD27 DNA repair genes. Mol Gen Genet 253(6):655-65 SGD PMID 9079876
  4. Qiu J, et al. (1998) Saccharomyces cerevisiae exonuclease-1 plays a role in UV resistance that is distinct from nucleotide excision repair. Nucleic Acids Res 26(13):3077-83 SGD PMID 9628902

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