YDR168W

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Systematic name YDR168W
Gene name CDC37
Aliases SMO1
Feature type ORF, Verified
Coordinates Chr IV:790328..791848
Primary SGDID S000002575


Description of YDR168W: Essential Hsp90p co-chaperone; necessary for passage through the START phase of the cell cycle; stabilizes protein kinase nascent chains and participates along with Hsp90p in their folding[1][2]




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References

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  1. Abbas-Terki T, et al. (2002) The Hsp90 co-chaperones Cdc37 and Sti1 interact physically and genetically. Biol Chem 383(9):1335-42 SGD PMID 12437126
  2. Mandal AK, et al. (2007) Cdc37 has distinct roles in protein kinase quality control that protect nascent chains from degradation and promote posttranslational maturation. J Cell Biol 176(3):319-28 SGD PMID 17242065

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