YDR162C

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Systematic name YDR162C
Gene name NBP2
Aliases
Feature type ORF, Verified
Coordinates Chr IV:781100..780390
Primary SGDID S000002569


Description of YDR162C: Protein involved in the HOG (high osmolarity glycerol) pathway, negatively regulates Hog1p by recruitment of phosphatase Ptc1p the Pbs2p-Hog1p complex, found in the nucleus and cytoplasm, contains an SH3 domain that binds Pbs2p[1][2]




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References

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  1. Mapes J and Ota IM (2004) Nbp2 targets the Ptc1-type 2C Ser/Thr phosphatase to the HOG MAPK pathway. EMBO J 23(2):302-11 SGD PMID 14685261
  2. Ohkuni K, et al. (2003) Yeast Nap1-binding protein Nbp2p is required for mitotic growth at high temperatures and for cell wall integrity. Genetics 165(2):517-29 SGD PMID 14573466

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