YDR098C
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| Systematic name | YDR098C |
| Gene name | GRX3 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:645035..644178 |
| Primary SGDID | S000002505 |
Description of YDR098C: Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx4p and Grx5p; protects cells from oxidative damage; evidence exists indicating that the translation start site is not Met1 as currently annotated, but rather Met36[1][2][3]
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References
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- ↑ Dingra NN (2005) Characterization of the Role of Glutaredoxin 3 and its Binding Partners in Maintaining Iron Homeostasis in Saccharomyces cerevisiae () SGD PMID
- ↑ Li H, et al. (2009) The yeast iron regulatory proteins Grx3/4 and Fra2 form heterodimeric complexes containing a [2Fe-2S] cluster with cysteinyl and histidyl ligation. Biochemistry 48(40):9569-81 SGD PMID 19715344
- ↑ Rodriguez-Manzaneque MT, et al. (1999) Grx5 glutaredoxin plays a central role in protection against protein oxidative damage in Saccharomyces cerevisiae. Mol Cell Biol 19(12):8180-90 SGD PMID 10567543
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