YDR034C

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Systematic name YDR034C
Gene name LYS14
Aliases
Feature type ORF, Verified
Coordinates Chr IV:512109..509737
Primary SGDID S000002441


Description of YDR034C: Transcriptional activator involved in regulation of genes of the lysine biosynthesis pathway; requires 2-aminoadipate semialdehyde as co-inducer[1][2][3][4]




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References

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  1. Becker B, et al. (1998) A nonameric core sequence is required upstream of the LYS genes of Saccharomyces cerevisiae for Lys14p-mediated activation and apparent repression by lysine. Mol Microbiol 29(1):151-63 SGD PMID 9701810
  2. El Alami M, et al. (2002) The proper folding of a long C-terminal segment of the yeast Lys14p regulator is required for activation of LYS genes in response to the metabolic effector. Mol Microbiol 43(6):1629-39 SGD PMID 11952910
  3. Feller A, et al. (1994) Repression of the genes for lysine biosynthesis in Saccharomyces cerevisiae is caused by limitation of Lys14-dependent transcriptional activation. Mol Cell Biol 14(10):6411-8 SGD PMID 7935367
  4. Ramos F, et al. (1988) Control of enzyme synthesis in the lysine biosynthetic pathway of Saccharomyces cerevisiae. Evidence for a regulatory role of gene LYS14. Eur J Biochem 171(1-2):171-6 SGD PMID 3123231

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