YDR019C

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Systematic name YDR019C
Gene name GCV1
Aliases GSD1
Feature type ORF, Verified
Coordinates Chr IV:485365..484163
Primary SGDID S000002426


Description of YDR019C: T subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF; expression is regulated by levels of levels of 5,10-methylene-THF in the cytoplasm[1][2][3]




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References

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  1. Gelling CL, et al. (2004) Identification of a novel one-carbon metabolism regulon in Saccharomyces cerevisiae. J Biol Chem 279(8):7072-81 SGD PMID 14645232
  2. McNeil JB, et al. (1997) Cloning, and molecular characterization of the GCV1 gene encoding the glycine cleavage T-protein from Saccharomyces cerevisiae. Gene 186(1):13-20 SGD PMID 9047339
  3. Piper MD, et al. (2000) Regulation of the balance of one-carbon metabolism in Saccharomyces cerevisiae. J Biol Chem 275(40):30987-95 SGD PMID 10871621

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