YDL201W
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| Systematic name | YDL201W |
| Gene name | TRM8 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:99561..100421 |
| Primary SGDID | S000002360 |
Description of YDL201W: Noncatalytic subunit of a tRNA methyltransferase complex; Trm8p and Trm82p comprise an enzyme that catalyzes a methyl-transfer from S-adenosyl-l-methionine to the N(7) atom of guanine at position 46 in tRNA; Trm8 lacks catalytic activity if not bound to Trm82p[1][2][3][4]
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References
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- ↑ Alexandrov A, et al. (2002) Two proteins that form a complex are required for 7-methylguanosine modification of yeast tRNA. RNA 8(10):1253-66 SGD PMID 12403464
- ↑ Leulliot N, et al. (2008) Structure of the Yeast tRNA m7G Methylation Complex. Structure 16(1):52-61 SGD PMID 18184583
- ↑ Matsumoto K, et al. (2007) RNA recognition mechanism of eukaryote tRNA (m(7)G46) methyltransferase (Trm8-Trm82 complex). FEBS Lett 581(8):1599-604 SGD PMID 17382321
- ↑ Matsumoto K, et al. (2008) Production of yeast tRNA (m(7)G46) methyltransferase (Trm8-Trm82 complex) in a wheat germ cell-free translation system. J Biotechnol 133(4):453-60 SGD PMID 18164779
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