YDL188C

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Systematic name YDL188C
Gene name PPH22
Aliases PPH2
Feature type ORF, Verified
Coordinates Chr IV:124998..123865
Primary SGDID S000002347


Description of YDL188C: Catalytic subunit of protein phosphatase 2A (PP2A), functionally redundant with Pph21p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis[1][2][3][4]




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References

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  1. Sneddon AA, et al. (1990) Saccharomyces cerevisiae protein phosphatase 2A performs an essential cellular function and is encoded by two genes. EMBO J 9(13):4339-46 SGD PMID 2176150
  2. Stark MJ (1996) Yeast protein serine/threonine phosphatases: multiple roles and diverse regulation. Yeast 12(16):1647-75 SGD PMID 9123967
  3. Wei H, et al. (2001) Carboxymethylation of the PP2A catalytic subunit in Saccharomyces cerevisiae is required for efficient interaction with the B-type subunits Cdc55p and Rts1p. J Biol Chem 276(2):1570-7 SGD PMID 11038366
  4. Zabrocki P, et al. (2002) Protein phosphatase 2A on track for nutrient-induced signalling in yeast. Mol Microbiol 43(4):835-42 SGD PMID 11929536

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