YDL156W

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Systematic name YDL156W
Gene name CMR1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:174918..176486
Primary SGDID S000002315


Description of YDL156W: DNA-binding protein with preference for UV-damaged DNA; protein sequence contains three WD domains (WD-40 repeat); green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; potential regulatory target of Mbp1p, which binds to the promoter region; co-localizes with Hos2p in nuclear foci in response to DNA damage by MMS[1][2][3][4][5]




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References

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  1. Jump up Brohee S, et al. (2011) Unraveling networks of co-regulated genes on the sole basis of genome sequences. Nucleic Acids Res () SGD PMID 21572103
  2. Jump up Choi DH, et al. (2012) Saccharomyces cerevisiae Cmr1 protein preferentially binds to UV-damaged DNA in vitro. J Microbiol 50(1):112-8 SGD PMID 22367945
  3. Jump up Hellauer K, et al. (2005) Large-scale analysis of genes that alter sensitivity to the anticancer drug tirapazamine in Saccharomyces cerevisiae. Mol Pharmacol 68(5):1365-75 SGD PMID 16061773
  4. Jump up Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
  5. Jump up Tkach JM, et al. (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress.LID - 10.1038/ncb2549 [doi] Nat Cell Biol () SGD PMID 22842922

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