YDL147W

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Systematic name YDL147W
Gene name RPN5
Aliases NAS5
Feature type ORF, Verified
Coordinates Chr IV:190924..192261
Primary SGDID S000002306


Description of YDL147W: Subunit of the COP9 signalosome (CSN) and non-ATPase regulatory subunit of the 26S proteasome lid, similar to mammalian p55 subunit and to another S. cerevisiae regulatory subunit, Rpn7p; Rpn5p is an essential protein[1][2][3]




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References

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  1. Glickman MH, et al. (1998) The regulatory particle of the Saccharomyces cerevisiae proteasome. Mol Cell Biol 18(6):3149-62 SGD PMID 9584156
  2. Saito A, et al. (1997) cDNA cloning and functional analysis of p44.5 and p55, two regulatory subunits of the 26S proteasome. Gene 203(2):241-50 SGD PMID 9426256
  3. Yu Z, et al. (2011) Dual function of Rpn5 in two PCI complexes, the 26S proteasome and COP9 signalosome. Mol Biol Cell 22(7):911-20 SGD PMID 21289098

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