YDL101C
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| Systematic name | YDL101C |
| Gene name | DUN1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:281848..280307 |
| Primary SGDID | S000002259 |
Description of YDL101C: Cell-cycle checkpoint serine-threonine kinase required for DNA damage-induced transcription of certain target genes, phosphorylation of Rad55p and Sml1p, and transient G2/M arrest after DNA damage; also regulates postreplicative DNA repair[1][2][3][4]
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References
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- ↑ Bashkirov VI, et al. (2003) Direct kinase-to-kinase signaling mediated by the FHA phosphoprotein recognition domain of the Dun1 DNA damage checkpoint kinase. Mol Cell Biol 23(4):1441-52 SGD PMID 12556502
- ↑ Blanchard H, et al. (2001) Crystallization and preliminary X-ray diffraction studies of FHA domains of Dun1 and Rad53 protein kinases. Acta Crystallogr D Biol Crystallogr 57(Pt 3):459-61 SGD PMID 11223532
- ↑ Hammet A, et al. (2002) Posttranscriptional regulation of the RAD5 DNA repair gene by the Dun1 kinase and the Pan2-Pan3 poly(A)-nuclease complex contributes to survival of replication blocks. J Biol Chem 277(25):22469-74 SGD PMID 11953437
- ↑ Zhao X and Rothstein R (2002) The Dun1 checkpoint kinase phosphorylates and regulates the ribonucleotide reductase inhibitor Sml1. Proc Natl Acad Sci U S A 99(6):3746-51 SGD PMID 11904430
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