YDL065C

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Systematic name YDL065C
Gene name PEX19
Aliases PAS12
Feature type ORF, Verified
Coordinates Chr IV:337277..336249
Primary SGDID S000002223


Description of YDL065C: Chaperone and import receptor for newly-synthesized class I PMPs; binds peroxisomal membrane proteins (PMPs) in the cytoplasm and delivers them to the peroxisome for subsequent insertion into the peroxisomal membrane; interacts with Myo2p and contributes to peroxisome partitioning[1][2][3][4]




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References

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  1. Fang Y, et al. (2004) PEX3 functions as a PEX19 docking factor in the import of class I peroxisomal membrane proteins. J Cell Biol 164(6):863-75 SGD PMID 15007061
  2. Gotte K, et al. (1998) Pex19p, a farnesylated protein essential for peroxisome biogenesis. Mol Cell Biol 18(1):616-28 SGD PMID 9418908
  3. Hettema EH, et al. (2000) Saccharomyces cerevisiae pex3p and pex19p are required for proper localization and stability of peroxisomal membrane proteins. EMBO J 19(2):223-33 SGD PMID 10637226
  4. Otzen M, et al. (2012) Pex19p contributes to peroxisome inheritance in the association of peroxisomes to Myo2p.LID - 10.1111/j.1600-0854.2012.01364.x [doi] Traffic () SGD PMID 22486971

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