YDL058W

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Systematic name YDL058W
Gene name USO1
Aliases INT1
Feature type ORF, Verified
Coordinates Chr IV:345665..351037
Primary SGDID S000002216


Description of YDL058W: Essential protein involved in the vesicle-mediated ER to Golgi transport step of secretion; binds membranes and functions during vesicle docking to the Golgi; required for assembly of the ER-to-Golgi SNARE complex[1][2][3][4]




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References

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  1. Cao X, et al. (1998) Initial docking of ER-derived vesicles requires Uso1p and Ypt1p but is independent of SNARE proteins. EMBO J 17(8):2156-65 SGD PMID 9545229
  2. Nakajima H, et al. (1991) A cytoskeleton-related gene, uso1, is required for intracellular protein transport in Saccharomyces cerevisiae. J Cell Biol 113(2):245-60 SGD PMID 2010462
  3. Noda Y, et al. (2007) Specific membrane recruitment of Uso1 protein, the essential endoplasmic reticulum-to-Golgi tethering factor in yeast vesicular transport. J Cell Biochem 101(3):686-94 SGD PMID 17192843
  4. Sapperstein SK, et al. (1996) Assembly of the ER to Golgi SNARE complex requires Uso1p. J Cell Biol 132(5):755-67 SGD PMID 8603910

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