YDL046W

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Systematic name YDL046W
Gene name NPC2
Aliases
Feature type ORF, Verified
Coordinates Chr IV:371240..371761
Primary SGDID S000002204


Description of YDL046W: Functional homolog of human NPC2/He1, which is a cholesterol-binding protein whose deficiency causes Niemann-Pick type C2 disease involving retention of cholesterol in lysosomes[1]




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References

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  1. Berger AC, et al. (2005) Saccharomyces cerevisiae Npc2p is a functionally conserved homologue of the human Niemann-Pick disease type C 2 protein, hNPC2. Eukaryot Cell 4(11):1851-62 SGD PMID 16278452

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