YCR076C
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| Systematic name | YCR076C |
| Gene name | FUB1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr III:250045..249293 |
| Primary SGDID | S000000672 |
Description of YCR076C: Putative protein of unknown function; interacts physically with multiple subunits of the 20S proteasome and genetically with genes encoding 20S core particle and 19S regulatory particle subunits; exhibits boundary activity which blocks the propagation of heterochromatic silencing; contains a PI31 proteasome regulator domain and sequence similarity with human PSMF1, a proteasome inhibitor; not an essential gene[1][2][3]
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References
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- Jump up ↑ Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 SGD PMID 12140549
- Jump up ↑ Hatanaka A, et al. (2011) Fub1p, a novel protein isolated by boundary screening, binds the proteasome complex. Genes Genet Syst 86(5):305-14 SGD PMID 22362029
- Jump up ↑ Oki M, et al. (2004) Barrier proteins remodel and modify chromatin to restrict silenced domains. Mol Cell Biol 24(5):1956-67 SGD PMID 14966276
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