YCR067C

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Systematic name YCR067C
Gene name SED4
Aliases
Feature type ORF, Verified
Coordinates Chr III:236322..233125
Primary SGDID S000000663


Description of YCR067C: Integral endoplasmic reticulum membrane protein that stimulates Sar1p GTPase activity; involved in COPII vesicle budding through disassociation of coat proteins from membranes onto liposomes; binds Sec16p; similar to Sec12p[1][2][3]




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References

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  1. Gimeno RE, et al. (1995) SED4 encodes a yeast endoplasmic reticulum protein that binds Sec16p and participates in vesicle formation. J Cell Biol 131(2):325-38 SGD PMID 7593162
  2. Hardwick KG, et al. (1992) Genes that allow yeast cells to grow in the absence of the HDEL receptor. EMBO J 11(11):4187-95 SGD PMID 1327759
  3. Kodera C, et al. (2011) Sed4p stimulates sar1p GTP hydrolysis and promotes limited coat disassembly. Traffic 12(5):591-9 SGD PMID 21291503

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