YCR057C
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| Systematic name | YCR057C |
| Gene name | PWP2 |
| Aliases | UTP1, YCR055C, YCR058C |
| Feature type | ORF, Verified |
| Coordinates | Chr III:223228..220457 |
| Primary SGDID | S000000653 |
Description of YCR057C: Conserved 90S pre-ribosomal component essential for proper endonucleolytic cleavage of the 35 S rRNA precursor at A0, A1, and A2 sites; contains eight WD-repeats; PWP2 deletion leads to defects in cell cycle and bud morphogenesis[1][2]
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References
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- Jump up ↑ Dosil M and Bustelo XR (2004) Functional characterization of Pwp2, a WD family protein essential for the assembly of the 90 S pre-ribosomal particle. J Biol Chem 279(36):37385-97 SGD PMID 15231838
- Jump up ↑ Shafaatian R, et al. (1996) PWP2, a member of the WD-repeat family of proteins, is an essential Saccharomyces cerevisiae gene involved in cell separation. Mol Gen Genet 252(1-2):101-14 SGD PMID 8804409
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