YCR020W-B

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Systematic name YCR020W-B
Gene name HTL1
Aliases
Feature type ORF, Verified
Coordinates Chr III:155320..155556
Primary SGDID S000006439


Description of YCR020W-B: Component of the RSC chromatin remodeling complex; RSC functions in transcriptional regulation and elongation, chromosome stability, and establishing sister chromatid cohesion; involved in telomere maintenance[1][2][3][4][5][6]




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References

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  1. Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63 SGD PMID 15161972
  2. Baetz KK, et al. (2004) The ctf13-30/CTF13 genomic haploinsufficiency modifier screen identifies the yeast chromatin remodeling complex RSC, which is required for the establishment of sister chromatid cohesion. Mol Cell Biol 24(3):1232-44 SGD PMID 14729968
  3. Carey M, et al. (2006) RSC exploits histone acetylation to abrogate the nucleosomal block to RNA polymerase II elongation. Mol Cell 24(3):481-7 SGD PMID 17081996
  4. Lanzuolo C, et al. (2001) The HTL1 gene (YCR020W-b) of Saccharomyces cerevisiae is necessary for growth at 37 degrees C, and for the conservation of chromosome stability and fertility. Yeast 18(14):1317-30 SGD PMID 11571756
  5. Lu YM, et al. (2003) Dissecting the pet18 mutation in Saccharomyces cerevisiae: HTL1 encodes a 7-kDa polypeptide that interacts with components of the RSC complex. Mol Genet Genomics 269(3):321-30 SGD PMID 12684875
  6. Romeo MJ, et al. (2002) HTL1 encodes a novel factor that interacts with the RSC chromatin remodeling complex in Saccharomyces cerevisiae. Mol Cell Biol 22(23):8165-74 SGD PMID 12417720

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