YCL035C
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| Systematic name | YCL035C |
| Gene name | GRX1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr III:61173..60841 |
| Primary SGDID | S000000540 |
Description of YCL035C: Glutathione-dependent disulfide oxidoreductase; hydroperoxide and superoxide-radical responsive, heat-stable, with active site cysteine pair; protects cells from oxidative damage; GRX1 has a paralog, GRX2, that arose from the whole genome duplication[1][2][3]
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References
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- Jump up ↑ Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 SGD PMID 16169922
- Jump up ↑ Collinson EJ, et al. (2002) The yeast glutaredoxins are active as glutathione peroxidases. J Biol Chem 277(19):16712-7 SGD PMID 11875065
- Jump up ↑ Luikenhuis S, et al. (1998) The yeast Saccharomyces cerevisiae contains two glutaredoxin genes that are required for protection against reactive oxygen species. Mol Biol Cell 9(5):1081-91 SGD PMID 9571241
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