YCL024W

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Systematic name YCL024W
Gene name KCC4
Aliases
Feature type ORF, Verified
Coordinates Chr III:79162..82275
Primary SGDID S000000529


Description of YCL024W: Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication[1][2][3][4]




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References

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  1. Barral Y, et al. (1999) Nim1-related kinases coordinate cell cycle progression with the organization of the peripheral cytoskeleton in yeast. Genes Dev 13(2):176-87 SGD PMID 9925642
  2. Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 SGD PMID 16169922
  3. Okuzaki D and Nojima H (2001) Kcc4 associates with septin proteins of Saccharomyces cerevisiae. FEBS Lett 489(2-3):197-201 SGD PMID 11165249
  4. Okuzaki D, et al. (2003) The Saccharomyces cerevisiae bud-neck proteins Kcc4 and Gin4 have distinct but partially-overlapping cellular functions. Genes Genet Syst 78(2):113-26 SGD PMID 12773812

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