YCL010C

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Systematic name YCL010C
Gene name SGF29
Aliases
Feature type ORF, Verified
Coordinates Chr III:104350..103571
Primary SGDID S000000516


Description of YCL010C: Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes; HAT/Core module also contains Gcn5p, Ngg1p, and Ada2p; binds methylated histone H3K4; involved in transcriptional regulation through SAGA and TBP recruitment to target promoters and H3 acetylation[1][2][3][4]




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References

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  1. Jump up Bian C, et al. (2011) Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.LID - 10.1038/emboj.2011.193 [doi] EMBO J () SGD PMID 21685874
  2. Jump up Lee KK, et al. (2011) Combinatorial depletion analysis to assemble the network architecture of the SAGA and ADA chromatin remodeling complexes. Mol Syst Biol 7():503 SGD PMID 21734642
  3. Jump up Sanders SL, et al. (2002) Proteomics of the eukaryotic transcription machinery: identification of proteins associated with components of yeast TFIID by multidimensional mass spectrometry. Mol Cell Biol 22(13):4723-38 SGD PMID 12052880
  4. Jump up Shukla A, et al. (2012) Sgf29p facilitates the recruitment of TATA box binding protein but does not alter SAGA's global structural integrity in vivo. Biochemistry 51(2):706-14 SGD PMID 22224423

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