YBR265W

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Systematic name YBR265W
Gene name TSC10
Aliases
Feature type ORF, Verified
Coordinates Chr II:738582..739544
Primary SGDID S000000469


Description of YBR265W: 3-ketosphinganine reductase, catalyzes the second step in phytosphingosine synthesis, essential for growth in the absence of exogenous dihydrosphingosine or phytosphingosine, member of short chain dehydrogenase/reductase protein family[1]




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References

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  1. Beeler T, et al. (1998) The Saccharomyces cerevisiae TSC10/YBR265w gene encoding 3-ketosphinganine reductase is identified in a screen for temperature-sensitive suppressors of the Ca2+-sensitive csg2Delta mutant. J Biol Chem 273(46):30688-94 SGD PMID 9804843

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