YBR173C

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Systematic name YBR173C
Gene name UMP1
Aliases RNS2
Feature type ORF, Verified
Coordinates Chr II:582172..581726
Primary SGDID S000000377


Description of YBR173C: Short-lived chaperone required for correct maturation of the 20S proteasome; may inhibit premature dimerization of proteasome half-mers; degraded by proteasome upon completion of its assembly[1][2][3][4]




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References

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  1. Jump up Bochtler M, et al. (1999) The proteasome. Annu Rev Biophys Biomol Struct 28:295-317 SGD PMID 10410804
  2. Jump up Li X, et al. (2007) beta-Subunit appendages promote 20S proteasome assembly by overcoming an Ump1-dependent checkpoint. EMBO J 26(9):2339-49 SGD PMID 17431397
  3. Jump up Maurizi MR (1998) Proteasome assembly: biting the hand. Curr Biol 8(13):R453-6 SGD PMID 9651672
  4. Jump up Ramos PC, et al. (1998) Ump1p is required for proper maturation of the 20S proteasome and becomes its substrate upon completion of the assembly. Cell 92(4):489-99 SGD PMID 9491890

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