Difference between revisions of "YAL061W"

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==References==
 
==References==
 
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Revision as of 06:20, 10 December 2019

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Systematic name YAL061W
Gene name BDH2
Aliases
Feature type ORF, Uncharacterized
Coordinates Chr I:33448..34701
Primary SGDID S000000057


Description of YAL061W: Putative medium-chain alcohol dehydrogenase with similarity to BDH1; transcription induced by constitutively active PDR1 and PDR3[1][2][3][4]







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Community Commentary

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This gene is part of the UW-Stout Orphan Gene Project. Learn more here.

Growth Curve

YAL061 YPD.png

In a BY4735 background, knocking out YAL061W seems to have a moderate effect on growth rate in log-phase. In this assay, the BY4735 strain's doubling time was 361 minutes, while the YAL061 knock-out strain's doubling time was 469 minutes. (These doubling times are the means of three experiments.)

Caffeine and Strand YAL061W

megan6.png

Wild Type and Caffeine

megan16.png





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References

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  1. Devaux F, et al. (2002) Genome-wide studies on the nuclear PDR3-controlled response to mitochondrial dysfunction in yeast. FEBS Lett 515(1-3):25-8 SGD PMID 11943188
  2. Dickinson JR, et al. (2003) The catabolism of amino acids to long chain and complex alcohols in Saccharomyces cerevisiae. J Biol Chem 278(10):8028-34 SGD PMID 12499363
  3. Gonzalez E, et al. (2000) Characterization of a (2R,3R)-2,3-butanediol dehydrogenase as the Saccharomyces cerevisiae YAL060W gene product. Disruption and induction of the gene. J Biol Chem 275(46):35876-85 SGD PMID 10938079
  4. do Valle Matta MA, et al. (2001) Novel target genes of the yeast regulator Pdr1p: a contribution of the TPO1 gene in resistance to quinidine and other drugs. Gene 272(1-2):111-9 SGD PMID 11470516

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