Difference between revisions of "YPR186C"

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'''Description of YPR186C:''' Transcription factor IIIA (TFIIIA), essential protein with nine C2H2 Zn-fingers, binds the 5S rRNA gene through the zinc finger domain and directs assembly of a multiprotein initiation complex for RNA polymerase III; also binds DNA<ref name='S000064745'>Pizzi S, et al. (1999) Domain organization and functional properties of yeast transcription factor IIIA species with different zinc stoichiometries. J Biol Chem 274(4):2539-48 {{SGDpaper|S000064745}} PMID 9891026</ref><ref name='S000056310'>Woychik NA and Young RA (1992) Genes encoding transcription factor IIIA and the RNA polymerase common subunit RPB6 are divergently transcribed in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 89(9):3999-4003
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'''Description of YPR186C:''' Transcription factor IIIA (TFIIIA); essential DNA binding protein required for transcription of 5S rRNA by RNA polymerase III; not involved in transcription of other RNAP III genes; nine conserved zinc fingers; may also bind 5S rRNA<ref name='S000064740'>Archambault J, et al. (1992) The deduced sequence of the transcription factor TFIIIA from Saccharomyces cerevisiae reveals extensive divergence from Xenopus TFIIIA. J Biol Chem 267(5):3282-8 {{SGDpaper|S000064740}} PMID 1737784</ref><ref name='S000064744'>Shastry BS (1996) Transcription factor IIIA (TFIIIA) in the second decade. J Cell Sci 109 ( Pt 3):535-9 {{SGDpaper|S000064744}} PMID 8907699</ref><ref name='S000116504'>Wang CK and Weil PA (1989) Purification and characterization of Saccharomyces cerevisiae transcription factor IIIA. J Biol Chem 264(2):1092-9 {{SGDpaper|S000116504}} PMID 2642897</ref><ref name='S000056310'>Woychik NA and Young RA (1992) Genes encoding transcription factor IIIA and the RNA polymerase common subunit RPB6 are divergently transcribed in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 89(9):3999-4003
 
  {{SGDpaper|S000056310}} PMID 1570325</ref>
 
  {{SGDpaper|S000056310}} PMID 1570325</ref>
 
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Revision as of 14:05, 3 May 2010

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Systematic name YPR186C
Gene name PZF1
Aliases TFC2
Feature type ORF, Verified
Coordinates Chr XVI:911018..909729
Primary SGDID S000006390


Description of YPR186C: Transcription factor IIIA (TFIIIA); essential DNA binding protein required for transcription of 5S rRNA by RNA polymerase III; not involved in transcription of other RNAP III genes; nine conserved zinc fingers; may also bind 5S rRNA[1][2][3][4]




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References

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  1. Archambault J, et al. (1992) The deduced sequence of the transcription factor TFIIIA from Saccharomyces cerevisiae reveals extensive divergence from Xenopus TFIIIA. J Biol Chem 267(5):3282-8 SGD PMID 1737784
  2. Shastry BS (1996) Transcription factor IIIA (TFIIIA) in the second decade. J Cell Sci 109 ( Pt 3):535-9 SGD PMID 8907699
  3. Wang CK and Weil PA (1989) Purification and characterization of Saccharomyces cerevisiae transcription factor IIIA. J Biol Chem 264(2):1092-9 SGD PMID 2642897
  4. Woychik NA and Young RA (1992) Genes encoding transcription factor IIIA and the RNA polymerase common subunit RPB6 are divergently transcribed in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 89(9):3999-4003 SGD PMID 1570325

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