YPR111W

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Systematic name YPR111W
Gene name DBF20
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:747304..748998
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Description of YPR111W: Ser/Thr kinase involved in late nuclear division, one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis[1][2][3]



Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [4] [5]


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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [4] [5]


References

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  1. Hwa Lim H, et al. (2003) Inactivation of mitotic kinase triggers translocation of MEN components to mother-daughter neck in yeast. Mol Biol Cell 14(11):4734-43 SGD PMID 12937277
  2. Menssen R, et al. (2001) Asymmetric spindle pole localization of yeast Cdc15 kinase links mitotic exit and cytokinesis. Curr Biol 11(5):345-50 SGD PMID 11267871
  3. Toyn JH and Johnston LH (1994) The Dbf2 and Dbf20 protein kinases of budding yeast are activated after the metaphase to anaphase cell cycle transition. EMBO J 13(5):1103-13 SGD PMID 8131744
  4. 4.0 4.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  5. 5.0 5.1 submitted by Jeff Ubersax on 2004-01-29

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