Difference between revisions of "YPL155C"

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'''Description of YPL155C:''' Kinesin-related motor protein involved in mitotic spindle positioning, stabilizes microtubules by targeting Bik1p to the plus end; Kip2p levels are controlled during the cell cycle<ref name='S000076751'>Carvalho P, et al. (2004) Cell cycle control of kinesin-mediated transport of Bik1 (CLIP-170) regulates microtubule stability and dynein activation. Dev Cell 6(6):815-29 {{SGDpaper|S000076751}} PMID 15177030</ref><ref name='S000042553'>Cottingham FR and Hoyt MA (1997) Mitotic spindle positioning in Saccharomyces cerevisiae is accomplished by antagonistically acting microtubule motor proteins. J Cell Biol 138(5):1041-53
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'''Description of YPL155C:''' Kinesin-related motor protein involved in mitotic spindle positioning, stabilizes microtubules by targeting Bik1p to the plus end; Kip2p levels are controlled during the cell cycle<ref name='S000042553'>Cottingham FR and Hoyt MA (1997) Mitotic spindle positioning in Saccharomyces cerevisiae is accomplished by antagonistically acting microtubule motor proteins. J Cell Biol 138(5):1041-53 {{SGDpaper|S000042553}} PMID 9281582</ref><ref name='S000076751'>Carvalho P, et al. (2004) Cell cycle control of kinesin-mediated transport of Bik1 (CLIP-170) regulates microtubule stability and dynein activation. Dev Cell 6(6):815-29
{{SGDpaper|S000042553}} PMID 9281582</ref>
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{{SGDpaper|S000076751}} PMID 15177030</ref>
 
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Revision as of 14:05, 31 March 2009

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Systematic name YPL155C
Gene name KIP2
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:259335..257215
Primary SGDID S000006076


Description of YPL155C: Kinesin-related motor protein involved in mitotic spindle positioning, stabilizes microtubules by targeting Bik1p to the plus end; Kip2p levels are controlled during the cell cycle[1][2]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [3] [4]





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References

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  1. Cottingham FR and Hoyt MA (1997) Mitotic spindle positioning in Saccharomyces cerevisiae is accomplished by antagonistically acting microtubule motor proteins. J Cell Biol 138(5):1041-53 SGD PMID 9281582
  2. Carvalho P, et al. (2004) Cell cycle control of kinesin-mediated transport of Bik1 (CLIP-170) regulates microtubule stability and dynein activation. Dev Cell 6(6):815-29 SGD PMID 15177030
  3. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  4. submitted by Jeff Ubersax on 2004-01-29

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