YPL110C

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Systematic name YPL110C
Gene name GDE1
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:344738..341067
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Description of YPL110C: Glycerophosphocholine (GroPCho) phosphodiesterase; hydrolyzes GroPCho to choline and glycerolphosphate, for use as a phosphate source and as a precursor for phosphocholine synthesis; may interact with ribosomes[1][2][3]



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References

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  1. Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 SGD PMID 16702403
  2. Fisher E, et al. (2005) Glycerophosphocholine-dependent growth requires Gde1p (YPL110c) and Git1p in Saccharomyces cerevisiae. J Biol Chem 280(43):36110-7 SGD PMID 16141200
  3. Fernandez-Murray JP and McMaster CR (2005) Glycerophosphocholine catabolism as a new route for choline formation for phosphatidylcholine synthesis by the Kennedy pathway. J Biol Chem 280(46):38290-6 SGD PMID 16172116

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