YPL094C
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Systematic name | YPL094C | |
Gene name | SEC62 | |
Aliases | LPG14 | |
Feature type | ORF, Verified | |
Coordinates | Chr XVI:370660..369836 | |
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Description of YPL094C: Essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER[1][2][3]
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References
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- ↑ Willer M, et al. (2003) Identification of novel protein-protein interactions at the cytosolic surface of the Sec63 complex in the yeast ER membrane. Yeast 20(2):133-48 SGD PMID 12518317
- ↑ Young BP, et al. (2001) Sec63p and Kar2p are required for the translocation of SRP-dependent precursors into the yeast endoplasmic reticulum in vivo. EMBO J 20(1-2):262-71 SGD PMID 11226176
- ↑ Deshaies RJ and Schekman R (1989) SEC62 encodes a putative membrane protein required for protein translocation into the yeast endoplasmic reticulum. J Cell Biol 109(6 Pt 1):2653-64 SGD PMID 2687286
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