Difference between revisions of "YPL093W"

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'''Description of YPL093W:''' Putative GTPase that associates with free 60S ribosomal subunits in the nucleolus and is required for 60S ribosomal subunit biogenesis; constituent of 66S pre-ribosomal particles; member of the ODN family of nucleolar G-proteins<ref name='S000076470'>Horsey EW, et al. (2004) Role of the yeast Rrp1 protein in the dynamics of pre-ribosome maturation. RNA 10(5):813-27 {{SGDpaper|S000076470}} PMID 15100437</ref><ref name='S000073608'>Kallstrom G, et al. (2003) The putative GTPases Nog1p and Lsg1p are required for 60S ribosomal subunit biogenesis and are localized to the nucleus and cytoplasm, respectively. Mol Cell Biol 23(12):4344-55 {{SGDpaper|S000073608}} PMID 12773575</ref><ref name='S000059087'>Park JH, et al. (2001) A novel nucleolar G-protein conserved in eukaryotes. J Cell Sci 114(Pt 1):173-185
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'''Description of YPL093W:''' Putative GTPase that associates with free 60S ribosomal subunits in the nucleolus and is required for 60S ribosomal subunit biogenesis; constituent of 66S pre-ribosomal particles; member of the ODN family of nucleolar G-proteins<ref name='S000059087'>Park JH, et al. (2001) A novel nucleolar G-protein conserved in eukaryotes. J Cell Sci 114(Pt 1):173-185 {{SGDpaper|S000059087}} PMID 11112701</ref><ref name='S000076470'>Horsey EW, et al. (2004) Role of the yeast Rrp1 protein in the dynamics of pre-ribosome maturation. RNA 10(5):813-27 {{SGDpaper|S000076470}} PMID 15100437</ref><ref name='S000073608'>Kallstrom G, et al. (2003) The putative GTPases Nog1p and Lsg1p are required for 60S ribosomal subunit biogenesis and are localized to the nucleus and cytoplasm, respectively. Mol Cell Biol 23(12):4344-55
{{SGDpaper|S000059087}} PMID 11112701</ref>
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{{SGDpaper|S000073608}} PMID 12773575</ref>
 
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Revision as of 14:05, 31 March 2009

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Systematic name YPL093W
Gene name NOG1
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:370975..372918
Primary SGDID S000006014


Description of YPL093W: Putative GTPase that associates with free 60S ribosomal subunits in the nucleolus and is required for 60S ribosomal subunit biogenesis; constituent of 66S pre-ribosomal particles; member of the ODN family of nucleolar G-proteins[1][2][3]




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Community Commentary

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Interactions

Genetic

YPL093W is suppressed by NSA2

Mutation type(s): Thermosensitive, overexpression

[4] [5]

Two Hybrid

Two Hybrid interaction with NSA2
[4] [5]





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References

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  1. Park JH, et al. (2001) A novel nucleolar G-protein conserved in eukaryotes. J Cell Sci 114(Pt 1):173-185 SGD PMID 11112701
  2. Horsey EW, et al. (2004) Role of the yeast Rrp1 protein in the dynamics of pre-ribosome maturation. RNA 10(5):813-27 SGD PMID 15100437
  3. Kallstrom G, et al. (2003) The putative GTPases Nog1p and Lsg1p are required for 60S ribosomal subunit biogenesis and are localized to the nucleus and cytoplasm, respectively. Mol Cell Biol 23(12):4344-55 SGD PMID 12773575
  4. 4.0 4.1 Lebreton A, et al. (2006) Nsa2 is an unstable, conserved factor required for the maturation of 27 SB pre-rRNAs. J Biol Chem 281(37):27099-108 SGD PMID 16861225
  5. 5.0 5.1 submitted by Alice Lebreton on 2006-08-01

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