Difference between revisions of "YPL063W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005984 YPL063W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TIM50 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TIM50 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XVI: | + | |nowrap| Chr XVI:429939..431369 |
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005984 | ||
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| − | '''Description of | + | '''Description of YPL063W:''' Essential component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); acts as receptor for the TIM23 complex guiding incoming precursors from the TOM complex; may control the gating of the Tim23p-Tim17p channel<ref name='S000081217'>Chacinska A, et al. (2005) Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17. Cell 120(6):817-29 {{SGDpaper|S000081217}} PMID 15797382</ref><ref name='S000129490'>Gevorkyan-Airapetov L, et al. (2009) Interaction of Tim23 with Tim50 Is Essential for Protein Translocation by the Mitochondrial TIM23 Complex. J Biol Chem 284(8):4865-72 {{SGDpaper|S000129490}} PMID 19017642</ref><ref name='S000130905'>Meinecke M, et al. (2006) Tim50 maintains the permeability barrier of the mitochondrial inner membrane. Science 312(5779):1523-6 {{SGDpaper|S000130905}} PMID 16763150</ref><ref name='S000129489'>Mokranjac D, et al. (2009) Role of Tim50 in the transfer of precursor proteins from the outer to the inner membrane of mitochondria. Mol Biol Cell 20(5):1400-7 |
| − | {{SGDpaper| | + | {{SGDpaper|S000129489}} PMID 19144822</ref> |
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| + | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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<protect> | <protect> | ||
Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YPL063W |
| Gene name | TIM50 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:429939..431369 |
| Primary SGDID | S000005984 |
Description of YPL063W: Essential component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); acts as receptor for the TIM23 complex guiding incoming precursors from the TOM complex; may control the gating of the Tim23p-Tim17p channel[1][2][3][4]
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Community Commentary
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Protein Details
Protein Localization
Protein identified in a purified mitochondrial extract. [5] [6]
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References
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- ↑ Chacinska A, et al. (2005) Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17. Cell 120(6):817-29 SGD PMID 15797382
- ↑ Gevorkyan-Airapetov L, et al. (2009) Interaction of Tim23 with Tim50 Is Essential for Protein Translocation by the Mitochondrial TIM23 Complex. J Biol Chem 284(8):4865-72 SGD PMID 19017642
- ↑ Meinecke M, et al. (2006) Tim50 maintains the permeability barrier of the mitochondrial inner membrane. Science 312(5779):1523-6 SGD PMID 16763150
- ↑ Mokranjac D, et al. (2009) Role of Tim50 in the transfer of precursor proteins from the outer to the inner membrane of mitochondria. Mol Biol Cell 20(5):1400-7 SGD PMID 19144822
- ↑ Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 SGD PMID 14597615
- ↑ submitted by Steffen Ohlmeier on 2004-04-08
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