Difference between revisions of "YPL024W"
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| − | '''Description of YPL024W:''' | + | '''Description of YPL024W:''' Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex; stimulates superhelical relaxing and ssDNA binding activities of Top3p; involved in response to DNA damage; null mutants display increased rates of recombination and delayed S phase<ref name='S000123855'>Chen CF and Brill SJ (2007) Binding and activation of DNA topoisomerase III by the Rmi1 subunit. J Biol Chem 282(39):28971-9 {{SGDpaper|S000123855}} PMID 17693398</ref><ref name='S000081006'>Chang M, et al. (2005) RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex. EMBO J 24(11):2024-33 |
{{SGDpaper|S000081006}} PMID 15889139</ref> | {{SGDpaper|S000081006}} PMID 15889139</ref> | ||
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Revision as of 07:21, 26 February 2009
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| Systematic name | YPL024W |
| Gene name | RMI1 |
| Aliases | NCE4 |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:503515..504240 |
| Primary SGDID | S000005945 |
Description of YPL024W: Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex; stimulates superhelical relaxing and ssDNA binding activities of Top3p; involved in response to DNA damage; null mutants display increased rates of recombination and delayed S phase[1][2]
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References
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- ↑ Chen CF and Brill SJ (2007) Binding and activation of DNA topoisomerase III by the Rmi1 subunit. J Biol Chem 282(39):28971-9 SGD PMID 17693398
- ↑ Chang M, et al. (2005) RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex. EMBO J 24(11):2024-33 SGD PMID 15889139
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