Difference between revisions of "YOR308C"

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'''Description of YOR308C:''' Component of the U4/U6.U5 snRNP complex involved in pre-mRNA splicing via spliceosome; has homology to human SART-1 and to an S. pombe protein; snu66 null mutation confers cold-sensitivity but is not lethal at normal growth temperatures<ref name='S000056376'>Stevens SW and Abelson J (1999) Purification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins. Proc Natl Acad Sci U S A 96(13):7226-31 {{SGDpaper|S000056376}} PMID 10377396</ref><ref name='S000066234'>Stevens SW, et al. (2001) Biochemical and genetic analyses of the U5, U6, and U4/U6 x U5 small nuclear ribonucleoproteins from Saccharomyces cerevisiae. RNA 7(11):1543-53
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'''Description of YOR308C:''' Component of the U4/U6.U5 snRNP complex involved in pre-mRNA splicing via spliceosome; also required for pre-5S rRNA processing and may act in concert with Rnh70p; has homology to human SART-1<ref name='S000131880'>Li Z, et al. (2009) Rational extension of the ribosome biogenesis pathway using network-guided genetics. PLoS Biol 7(10):e1000213 {{SGDpaper|S000131880}} PMID 19806183</ref><ref name='S000056376'>Stevens SW and Abelson J (1999) Purification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins. Proc Natl Acad Sci U S A 96(13):7226-31 {{SGDpaper|S000056376}} PMID 10377396</ref><ref name='S000066234'>Stevens SW, et al. (2001) Biochemical and genetic analyses of the U5, U6, and U4/U6 x U5 small nuclear ribonucleoproteins from Saccharomyces cerevisiae. RNA 7(11):1543-53
 
  {{SGDpaper|S000066234}} PMID 11720284</ref>
 
  {{SGDpaper|S000066234}} PMID 11720284</ref>
 
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Revision as of 14:05, 3 May 2010

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Systematic name YOR308C
Gene name SNU66
Aliases
Feature type ORF, Verified
Coordinates Chr XV:896384..894621
Primary SGDID S000005835


Description of YOR308C: Component of the U4/U6.U5 snRNP complex involved in pre-mRNA splicing via spliceosome; also required for pre-5S rRNA processing and may act in concert with Rnh70p; has homology to human SART-1[1][2][3]




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References

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  1. Li Z, et al. (2009) Rational extension of the ribosome biogenesis pathway using network-guided genetics. PLoS Biol 7(10):e1000213 SGD PMID 19806183
  2. Stevens SW and Abelson J (1999) Purification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins. Proc Natl Acad Sci U S A 96(13):7226-31 SGD PMID 10377396
  3. Stevens SW, et al. (2001) Biochemical and genetic analyses of the U5, U6, and U4/U6 x U5 small nuclear ribonucleoproteins from Saccharomyces cerevisiae. RNA 7(11):1543-53 SGD PMID 11720284

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