YOR232W

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Systematic name YOR232W
Gene name MGE1
Aliases GRPE, YGE1
Feature type ORF, Verified
Coordinates Chr XV:774574..775260
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Description of YOR232W: Protein of the mitochondrial matrix involved in protein import into mitochondria; acts as a cochaperone and a nucleotide release factor for Ssc1p; homolog of E. coli GrpE[1][2][3][4][5]



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References

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  1. Bolliger L, et al. (1994) A mitochondrial homolog of bacterial GrpE interacts with mitochondrial hsp70 and is essential for viability. EMBO J 13(8):1998-2006 SGD PMID 8168496
  2. Miao B, et al. (1997) Mge1 functions as a nucleotide release factor for Ssc1, a mitochondrial Hsp70 of Saccharomyces cerevisiae. J Mol Biol 265(5):541-52 SGD PMID 9048947
  3. Deloche O and Georgopoulos C (1996) Purification and biochemical properties of Saccharomyces cerevisiae's Mge1p, the mitochondrial cochaperone of Ssc1p. J Biol Chem 271(39):23960-6 SGD PMID 8798629
  4. Laloraya S, et al. (1994) A role for a eukaryotic GrpE-related protein, Mge1p, in protein translocation. Proc Natl Acad Sci U S A 91(14):6481-5 SGD PMID 8022808
  5. Ikeda E, et al. (1994) YGE1 is a yeast homologue of Escherichia coli grpE and is required for maintenance of mitochondrial functions. FEBS Lett 339(3):265-8 SGD PMID 8112465

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