Difference between revisions of "YOR037W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005563 YOR037W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CYC2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CYC2 '' | ||
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|nowrap| Chr XV:401555..402655 | |nowrap| Chr XV:401555..402655 | ||
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| − | | | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000005563 |
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| − | '''Description of | + | '''Description of YOR037W:''' Mitochondrial peripheral inner membrane protein, contains a FAD cofactor in a domain exposed in the intermembrane space; exhibits redox activity in vitro; likely participates in ligation of heme to acytochromes c and c1 (Cyc1p and Cyt1p)<ref name='S000075319'>Bernard DG, et al. (2003) Overlapping specificities of the mitochondrial cytochrome c and c1 heme lyases. J Biol Chem 278(50):49732-42 {{SGDpaper|S000075319}} PMID 14514677</ref><ref name='S000086902'>Bernard DG, et al. (2005) Cyc2p, a membrane-bound flavoprotein involved in the maturation of mitochondrial c-type cytochromes. J Biol Chem 280(48):39852-9 {{SGDpaper|S000086902}} PMID 16207709</ref><ref name='S000050483'>Pearce DA, et al. (1998) Cyc2p is required for maintaining ionic stability and efficient cytochrome c import and mitochondrial function in Saccharomyces cerevisiae. FEBS Lett 439(3):307-11 {{SGDpaper|S000050483}} PMID 9845343</ref><ref name='S000061363'>Sanchez NS, et al. (2001) Requirements of Cyc2p and the porin, Por1p, for ionic stability and mitochondrial integrity in Saccharomyces cerevisiae. Arch Biochem Biophys 392(2):326-32 |
| − | {{SGDpaper| | + | {{SGDpaper|S000061363}} PMID 11488609</ref> |
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__TOC__ | __TOC__ | ||
==Community Commentary== | ==Community Commentary== | ||
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| + | === Protein Details === | ||
| + | [[Category:Topic:Protein Details]] | ||
| + | ==== Protein Modification ==== | ||
| + | [[Category:Topic:Protein Details:Protein Modification]] | ||
| + | '''Modification(s)''': Phosphorylation [[Category:Modification:Phosphorylation]] | ||
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| + | Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. <ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref> <ref name = 'CAset7903-2004-01-29'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=7903 Jeff Ubersax] on 2004-01-29</ref> | ||
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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==References== | ==References== | ||
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Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YOR037W |
| Gene name | CYC2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:401555..402655 |
| Primary SGDID | S000005563 |
Description of YOR037W: Mitochondrial peripheral inner membrane protein, contains a FAD cofactor in a domain exposed in the intermembrane space; exhibits redox activity in vitro; likely participates in ligation of heme to acytochromes c and c1 (Cyc1p and Cyt1p)[1][2][3][4]
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Community Commentary
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [5] [6]
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References
See Help:References on how to add references
- ↑ Bernard DG, et al. (2003) Overlapping specificities of the mitochondrial cytochrome c and c1 heme lyases. J Biol Chem 278(50):49732-42 SGD PMID 14514677
- ↑ Bernard DG, et al. (2005) Cyc2p, a membrane-bound flavoprotein involved in the maturation of mitochondrial c-type cytochromes. J Biol Chem 280(48):39852-9 SGD PMID 16207709
- ↑ Pearce DA, et al. (1998) Cyc2p is required for maintaining ionic stability and efficient cytochrome c import and mitochondrial function in Saccharomyces cerevisiae. FEBS Lett 439(3):307-11 SGD PMID 9845343
- ↑ Sanchez NS, et al. (2001) Requirements of Cyc2p and the porin, Por1p, for ionic stability and mitochondrial integrity in Saccharomyces cerevisiae. Arch Biochem Biophys 392(2):326-32 SGD PMID 11488609
- ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ submitted by Jeff Ubersax on 2004-01-29
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