YOR026W
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| Systematic name | YOR026W |
| Gene name | BUB3 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:379781..380806 |
Description of YOR026W: Kinetochore checkpoint WD40 repeat protein that localizes to kinetochores during prophase and metaphase, delays anaphase in the presence of unattached kinetochores; forms complexes with Mad1p-Bub1p and with Cdc20p, binds Mad2p and Mad3p[1][2][3][4]
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References
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- ↑ Fraschini R, et al. (2001) Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores. EMBO J 20(23):6648-59 SGD PMID 11726501
- ↑ Hardwick KG, et al. (2000) MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p. J Cell Biol 148(5):871-82 SGD PMID 10704439
- ↑ Brady DM and Hardwick KG (2000) Complex formation between Mad1p, Bub1p and Bub3p is crucial for spindle checkpoint function. Curr Biol 10(11):675-8 SGD PMID 10837255
- ↑ Martinez-Exposito MJ, et al. (1999) Retention of the BUB3 checkpoint protein on lagging chromosomes. Proc Natl Acad Sci U S A 96(15):8493-8 SGD PMID 10411903
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