Difference between revisions of "YOR026W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005552 YOR026W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''BUB3 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''BUB3 '' | ||
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| − | '''Description of YOR026W:''' Kinetochore checkpoint WD40 repeat protein that localizes to kinetochores during prophase and metaphase, delays anaphase in the presence of unattached kinetochores; forms complexes with Mad1p-Bub1p and with Cdc20p, binds Mad2p and Mad3p<ref name='S000079059'>Fraschini R, et al. (2001) Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores. EMBO J 20(23):6648-59 {{SGDpaper|S000079059}} PMID 11726501</ref><ref name='S000056419'>Hardwick KG, et al. (2000) MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p. J Cell Biol 148(5):871-82 {{SGDpaper|S000056419}} PMID 10704439 | + | '''Description of YOR026W:''' Kinetochore checkpoint WD40 repeat protein that localizes to kinetochores during prophase and metaphase, delays anaphase in the presence of unattached kinetochores; forms complexes with Mad1p-Bub1p and with Cdc20p, binds Mad2p and Mad3p<ref name='S000053845'>Brady DM and Hardwick KG (2000) Complex formation between Mad1p, Bub1p and Bub3p is crucial for spindle checkpoint function. Curr Biol 10(11):675-8 {{SGDpaper|S000053845}} PMID 10837255</ref><ref name='S000079059'>Fraschini R, et al. (2001) Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores. EMBO J 20(23):6648-59 {{SGDpaper|S000079059}} PMID 11726501</ref><ref name='S000056419'>Hardwick KG, et al. (2000) MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p. J Cell Biol 148(5):871-82 {{SGDpaper|S000056419}} PMID 10704439</ref><ref name='S000053742'>Martinez-Exposito MJ, et al. (1999) Retention of the BUB3 checkpoint protein on lagging chromosomes. Proc Natl Acad Sci U S A 96(15):8493-8 |
{{SGDpaper|S000053742}} PMID 10411903</ref> | {{SGDpaper|S000053742}} PMID 10411903</ref> | ||
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Latest revision as of 07:45, 23 January 2012
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| Systematic name | YOR026W |
| Gene name | BUB3 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:379781..380806 |
| Primary SGDID | S000005552 |
Description of YOR026W: Kinetochore checkpoint WD40 repeat protein that localizes to kinetochores during prophase and metaphase, delays anaphase in the presence of unattached kinetochores; forms complexes with Mad1p-Bub1p and with Cdc20p, binds Mad2p and Mad3p[1][2][3][4]
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References
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- ↑ Brady DM and Hardwick KG (2000) Complex formation between Mad1p, Bub1p and Bub3p is crucial for spindle checkpoint function. Curr Biol 10(11):675-8 SGD PMID 10837255
- ↑ Fraschini R, et al. (2001) Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores. EMBO J 20(23):6648-59 SGD PMID 11726501
- ↑ Hardwick KG, et al. (2000) MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p. J Cell Biol 148(5):871-82 SGD PMID 10704439
- ↑ Martinez-Exposito MJ, et al. (1999) Retention of the BUB3 checkpoint protein on lagging chromosomes. Proc Natl Acad Sci U S A 96(15):8493-8 SGD PMID 10411903
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