YOL136C

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Systematic name YOL136C
Gene name PFK27
Aliases
Feature type ORF, Verified
Coordinates Chr XV:68754..67561
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Description of YOL136C: 6-phosphofructo-2-kinase, catalyzes synthesis of fructose-2,6-bisphosphate; inhibited by phosphoenolpyruvate and sn-glycerol 3-phosphate, expression induced by glucose and sucrose, transcriptional regulation involves protein kinase A[1][2][3][4]



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References

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  1. Bedri A, et al. (1989) Kinetics of 6-phosphofructo-2-kinase from Saccharomyces cerevisiae: inhibition of the enzyme by ATP. Biomed Biochim Acta 48(7):403-11 SGD PMID 2529854
  2. Kretschmer M, et al. (1993) Mutation of monofunctional 6-phosphofructo-2-kinase in yeast to bifunctional 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase. Biochemistry 32(41):11143-8 SGD PMID 8218176
  3. Goncalves PM, et al. (1997) Signalling pathways leading to transcriptional regulation of genes involved in the activation of glycolysis in yeast. Mol Microbiol 25(3):483-93 SGD PMID 9302011
  4. Boles E, et al. (1996) Cloning of a second gene encoding 5-phosphofructo-2-kinase in yeast, and characterization of mutant strains without fructose-2,6-bisphosphate. Mol Microbiol 20(1):65-76 SGD PMID 8861205

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