Difference between revisions of "YOL081W"
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| − | '''Description of YOL081W:''' GTPase-activating protein that negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions, has similarity to Ira1p and human neurofibromin | + | '''Description of YOL081W:''' GTPase-activating protein that negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions, has similarity to Ira1p and human neurofibromin<ref name='S000047724'>Tanaka K, et al. (1990) IRA2, a second gene of Saccharomyces cerevisiae that encodes a protein with a domain homologous to mammalian ras GTPase-activating protein. Mol Cell Biol 10(8):4303-13 {{SGDpaper|S000047724}} PMID 2164637</ref><ref name='S000052853'>Gil R and Seeling JM (1999) Characterization of Saccharomyces cerevisiae strains expressing ira1 mutant alleles modeled after disease-causing mutations in NF1. Mol Cell Biochem 202(1-2):109-18 |
| − | {{SGDpaper| | + | {{SGDpaper|S000052853}} PMID 10706001</ref> |
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Revision as of 14:05, 31 March 2009
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| Systematic name | YOL081W |
| Gene name | IRA2 |
| Aliases | CCS1, GLC4 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:171070..180309 |
| Primary SGDID | S000005441 |
Description of YOL081W: GTPase-activating protein that negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions, has similarity to Ira1p and human neurofibromin[1][2]
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References
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- ↑ Tanaka K, et al. (1990) IRA2, a second gene of Saccharomyces cerevisiae that encodes a protein with a domain homologous to mammalian ras GTPase-activating protein. Mol Cell Biol 10(8):4303-13 SGD PMID 2164637
- ↑ Gil R and Seeling JM (1999) Characterization of Saccharomyces cerevisiae strains expressing ira1 mutant alleles modeled after disease-causing mutations in NF1. Mol Cell Biochem 202(1-2):109-18 SGD PMID 10706001
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