YNL242W

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Systematic name YNL242W
Gene name ATG2
Aliases APG2, AUT8, SPO72
Feature type ORF, Verified
Coordinates Chr XIV:191325..196103
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Description of YNL242W: Peripheral membrane protein required for the formation of cytosolic sequestering vesicles involved in vacuolar import through both the Cvt pathway and autophagy; interacts with Atg9p and is necessary for its trafficking[1][2][3]



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References

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  1. Reggiori F, et al. (2004) The Atg1-Atg13 complex regulates Atg9 and Atg23 retrieval transport from the pre-autophagosomal structure. Dev Cell 6(1):79-90 SGD PMID 14723849
  2. Wang CW, et al. (2001) Apg2 is a novel protein required for the cytoplasm to vacuole targeting, autophagy, and pexophagy pathways. J Biol Chem 276(32):30442-51 SGD PMID 11382760
  3. Tsukada M and Ohsumi Y (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 333(1-2):169-74 SGD PMID 8224160

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