Difference between revisions of "YNL154C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YNL154C YNL154C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000005098 YNL154C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''YCK2 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''YCK2 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
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|nowrap| Chr XIV:345278..343638
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|nowrap| Chr XIV:345276..343636
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000005098
 
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'''Description of {{PAGENAME}}:''' Palmitoylated, plasma membrane-bound casein kinase I isoform; shares redundant functions with Yck1p in morphogenesis, proper septin assembly, endocytic trafficking; provides an essential function overlapping with that of Yck1p<ref name='S000076857'>Babu P, et al. (2004) Akr1p-dependent palmitoylation of Yck2p yeast casein kinase 1 is necessary and sufficient for plasma membrane targeting. J Biol Chem 279(26):27138-47 {{SGDpaper|S000076857}} PMID 15105419</ref><ref name='S000071693'>Roth AF, et al. (2002) The yeast DHHC cysteine-rich domain protein Akr1p is a palmitoyl transferase. J Cell Biol 159(1):23-8 {{SGDpaper|S000071693}} PMID 12370247</ref><ref name='S000061568'>Feng Y and Davis NG (2000) Akr1p and the type I casein kinases act prior to the ubiquitination step of yeast endocytosis: Akr1p is required for kinase localization to the plasma membrane. Mol Cell Biol 20(14):5350-9 {{SGDpaper|S000061568}} PMID 10866691</ref><ref name='S000053135'>Robinson LC, et al. (1999) The Yck2 yeast casein kinase 1 isoform shows cell cycle-specific localization to sites of polarized growth and is required for proper septin organization. Mol Biol Cell 10(4):1077-92 {{SGDpaper|S000053135}} PMID 10198058</ref><ref name='S000050372'>Robinson LC, et al. (1992) Yeast casein kinase I homologues: an essential gene pair. Proc Natl Acad Sci U S A 89(1):28-32 {{SGDpaper|S000050372}} PMID 1729698</ref><ref name='S000046342'>Robinson LC, et al. (1993) Casein kinase I-like protein kinases encoded by YCK1 and YCK2 are required for yeast morphogenesis. Mol Cell Biol 13(5):2870-81 {{SGDpaper|S000046342}} PMID 8474447</ref><ref name='S000042524'>Wang PC, et al. (1992) Two genes in Saccharomyces cerevisiae encode a membrane-bound form of casein kinase-1. Mol Biol Cell 3(3):275-86 {{SGDpaper|S000042524}} PMID 1627830</ref><ref name='S000041234'>Hicke L, et al. (1998) Cytoplasmic tail phosphorylation of the alpha-factor receptor is required for its ubiquitination and internalization. J Cell Biol 141(2):349-58 {{SGDpaper|S000041234}} PMID 9548714</ref><ref name='S000039637'>Marchal C, et al. (2000) Casein kinase I-dependent phosphorylation within a PEST sequence and ubiquitination at nearby lysines signal endocytosis of yeast uracil permease. J Biol Chem 275(31):23608-14
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'''Description of YNL154C:''' Palmitoylated plasma membrane-bound casein kinase I isoform; shares redundant functions with Yck1p in morphogenesis, proper septin assembly, endocytic trafficking; provides an essential function overlapping with that of Yck1p<ref name='S000076857'>Babu P, et al. (2004) Akr1p-dependent palmitoylation of Yck2p yeast casein kinase 1 is necessary and sufficient for plasma membrane targeting. J Biol Chem 279(26):27138-47 {{SGDpaper|S000076857}} PMID 15105419</ref><ref name='S000061568'>Feng Y and Davis NG (2000) Akr1p and the type I casein kinases act prior to the ubiquitination step of yeast endocytosis: Akr1p is required for kinase localization to the plasma membrane. Mol Cell Biol 20(14):5350-9 {{SGDpaper|S000061568}} PMID 10866691</ref><ref name='S000041234'>Hicke L, et al. (1998) Cytoplasmic tail phosphorylation of the alpha-factor receptor is required for its ubiquitination and internalization. J Cell Biol 141(2):349-58 {{SGDpaper|S000041234}} PMID 9548714</ref><ref name='S000039637'>Marchal C, et al. (2000) Casein kinase I-dependent phosphorylation within a PEST sequence and ubiquitination at nearby lysines signal endocytosis of yeast uracil permease. J Biol Chem 275(31):23608-14 {{SGDpaper|S000039637}} PMID 10811641</ref><ref name='S000050372'>Robinson LC, et al. (1992) Yeast casein kinase I homologues: an essential gene pair. Proc Natl Acad Sci U S A 89(1):28-32 {{SGDpaper|S000050372}} PMID 1729698</ref><ref name='S000046342'>Robinson LC, et al. (1993) Casein kinase I-like protein kinases encoded by YCK1 and YCK2 are required for yeast morphogenesis. Mol Cell Biol 13(5):2870-81 {{SGDpaper|S000046342}} PMID 8474447</ref><ref name='S000053135'>Robinson LC, et al. (1999) The Yck2 yeast casein kinase 1 isoform shows cell cycle-specific localization to sites of polarized growth and is required for proper septin organization. Mol Biol Cell 10(4):1077-92 {{SGDpaper|S000053135}} PMID 10198058</ref><ref name='S000071693'>Roth AF, et al. (2002) The yeast DHHC cysteine-rich domain protein Akr1p is a palmitoyl transferase. J Cell Biol 159(1):23-8 {{SGDpaper|S000071693}} PMID 12370247</ref><ref name='S000042524'>Wang PC, et al. (1992) Two genes in Saccharomyces cerevisiae encode a membrane-bound form of casein kinase-1. Mol Biol Cell 3(3):275-86
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  {{SGDpaper|S000039637}} PMID 10811641</ref>
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  {{SGDpaper|S000042524}} PMID 1627830</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Latest revision as of 07:45, 23 January 2012

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Systematic name YNL154C
Gene name YCK2
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:345276..343636
Primary SGDID S000005098


Description of YNL154C: Palmitoylated plasma membrane-bound casein kinase I isoform; shares redundant functions with Yck1p in morphogenesis, proper septin assembly, endocytic trafficking; provides an essential function overlapping with that of Yck1p[1][2][3][4][5][6][7][8][9]




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Community Commentary

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References

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  1. ↑ Babu P, et al. (2004) Akr1p-dependent palmitoylation of Yck2p yeast casein kinase 1 is necessary and sufficient for plasma membrane targeting. J Biol Chem 279(26):27138-47 SGD PMID 15105419
  2. ↑ Feng Y and Davis NG (2000) Akr1p and the type I casein kinases act prior to the ubiquitination step of yeast endocytosis: Akr1p is required for kinase localization to the plasma membrane. Mol Cell Biol 20(14):5350-9 SGD PMID 10866691
  3. ↑ Hicke L, et al. (1998) Cytoplasmic tail phosphorylation of the alpha-factor receptor is required for its ubiquitination and internalization. J Cell Biol 141(2):349-58 SGD PMID 9548714
  4. ↑ Marchal C, et al. (2000) Casein kinase I-dependent phosphorylation within a PEST sequence and ubiquitination at nearby lysines signal endocytosis of yeast uracil permease. J Biol Chem 275(31):23608-14 SGD PMID 10811641
  5. ↑ Robinson LC, et al. (1992) Yeast casein kinase I homologues: an essential gene pair. Proc Natl Acad Sci U S A 89(1):28-32 SGD PMID 1729698
  6. ↑ Robinson LC, et al. (1993) Casein kinase I-like protein kinases encoded by YCK1 and YCK2 are required for yeast morphogenesis. Mol Cell Biol 13(5):2870-81 SGD PMID 8474447
  7. ↑ Robinson LC, et al. (1999) The Yck2 yeast casein kinase 1 isoform shows cell cycle-specific localization to sites of polarized growth and is required for proper septin organization. Mol Biol Cell 10(4):1077-92 SGD PMID 10198058
  8. ↑ Roth AF, et al. (2002) The yeast DHHC cysteine-rich domain protein Akr1p is a palmitoyl transferase. J Cell Biol 159(1):23-8 SGD PMID 12370247
  9. ↑ Wang PC, et al. (1992) Two genes in Saccharomyces cerevisiae encode a membrane-bound form of casein kinase-1. Mol Biol Cell 3(3):275-86 SGD PMID 1627830

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