Difference between revisions of "YNL111C"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 13:02, 21 February 2007

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Systematic name YNL111C
Gene name CYB5
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:417304..416942


Description of YNL111C: Cytochrome b5, involved in the sterol and lipid biosynthesis pathways; required for sterol C5-6 and fatty acid desaturation[1][2][3]




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References

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  1. Rogers KM, et al. (2004) Disruption of the Candida albicans CYB5 gene results in increased azole sensitivity. Antimicrob Agents Chemother 48(9):3425-35 SGD PMID 15328107
  2. Ohba M, et al. (1979) Mutant and immunochemical studies on the involvement of cytochrome b5 in fatty acid desaturation by yeast microsomes. Biochim Biophys Acta 572(2):352-62 SGD PMID 106893
  3. Truan G, et al. (1994) Cloning and characterization of a yeast cytochrome b5-encoding gene which suppresses ketoconazole hypersensitivity in a NADPH-P-450 reductase-deficient strain. Gene 142(1):123-7 SGD PMID 8181746

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