Difference between revisions of "YMR246W"

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'''Description of YMR246W:''' Long chain fatty acyl-CoA synthetase, regulates protein modification during growth in the presence of ethanol, functions to incorporate palmitic acid into phospholipids and neutral lipids<ref name='S000039598'>Johnson DR, et al. (1994) Saccharomyces cerevisiae contains four fatty acid activation (FAA) genes: an assessment of their role in regulating protein N-myristoylation and cellular lipid metabolism. J Cell Biol 127(3):751-62 {{SGDpaper|S000039598}} PMID 7962057</ref><ref name='S000086973'>Nozawa M, et al. (2002) A role of Saccharomyces cerevisiae fatty Acid activation protein 4 in palmitoyl-CoA pool for growth in the presence of ethanol. J Biosci Bioeng 93(3):288-95
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'''Description of YMR246W:''' Long chain fatty acyl-CoA synthetase, activates imported fatty acids with a preference for C12:0-C16:0 chain lengths; functions in long chain fatty acid import; important for survival during stationary phase; localized to lipid particles<ref name='S000039598'>Johnson DR, et al. (1994) Saccharomyces cerevisiae contains four fatty acid activation (FAA) genes: an assessment of their role in regulating protein N-myristoylation and cellular lipid metabolism. J Cell Biol 127(3):751-62 {{SGDpaper|S000039598}} PMID 7962057</ref><ref name='S000048561'>Athenstaedt K, et al. (1999) Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae. J Bacteriol 181(20):6441-8 {{SGDpaper|S000048561}} PMID 10515935</ref><ref name='S000049471'>Ashrafi K, et al. (1998) A role for Saccharomyces cerevisiae fatty acid activation protein 4 in regulating protein N-myristoylation during entry into stationary phase. J Biol Chem 273(40):25864-74 {{SGDpaper|S000049471}} PMID 9748261</ref><ref name='S000073135'>Zou Z, et al. (2003) Vectorial acylation in Saccharomyces cerevisiae. Fat1p and fatty acyl-CoA synthetase are interacting components of a fatty acid import complex. J Biol Chem 278(18):16414-22
  {{SGDpaper|S000086973}} PMID 16233202</ref>
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  {{SGDpaper|S000073135}} PMID 12601005</ref>
 
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Revision as of 14:05, 11 February 2010

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Systematic name YMR246W
Gene name FAA4
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:759806..761890
Primary SGDID S000004860


Description of YMR246W: Long chain fatty acyl-CoA synthetase, activates imported fatty acids with a preference for C12:0-C16:0 chain lengths; functions in long chain fatty acid import; important for survival during stationary phase; localized to lipid particles[1][2][3][4]




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References

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  1. Johnson DR, et al. (1994) Saccharomyces cerevisiae contains four fatty acid activation (FAA) genes: an assessment of their role in regulating protein N-myristoylation and cellular lipid metabolism. J Cell Biol 127(3):751-62 SGD PMID 7962057
  2. Athenstaedt K, et al. (1999) Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae. J Bacteriol 181(20):6441-8 SGD PMID 10515935
  3. Ashrafi K, et al. (1998) A role for Saccharomyces cerevisiae fatty acid activation protein 4 in regulating protein N-myristoylation during entry into stationary phase. J Biol Chem 273(40):25864-74 SGD PMID 9748261
  4. Zou Z, et al. (2003) Vectorial acylation in Saccharomyces cerevisiae. Fat1p and fatty acyl-CoA synthetase are interacting components of a fatty acid import complex. J Biol Chem 278(18):16414-22 SGD PMID 12601005

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