Difference between revisions of "YMR189W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YMR189W YMR189W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004801 YMR189W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''GCV2 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''GCV2 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XIII:637499..640603
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|nowrap| Chr XIII:637500..640604
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000004801
 
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'''Description of {{PAGENAME}}:''' P subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF; expression is regulated by levels of levels of 5,10-methylene-THF in the cytoplasm<ref name='S000075481'>Gelling CL, et al. (2004) Identification of a novel one-carbon metabolism regulon in Saccharomyces cerevisiae. J Biol Chem 279(8):7072-81 {{SGDpaper|S000075481}} PMID 14645232</ref><ref name='S000056431'>Piper MD, et al. (2000) Regulation of the balance of one-carbon metabolism in Saccharomyces cerevisiae. J Biol Chem 275(40):30987-95 {{SGDpaper|S000056431}} PMID 10871621</ref><ref name='S000047381'>Sinclair DA, et al. (1996) Specific induction by glycine of the gene for the P-subunit of glycine decarboxylase from Saccharomyces cerevisiae. Mol Microbiol 19(3):611-23
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'''Description of YMR189W:''' P subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF; expression is regulated by levels of 5,10-methylene-THF in the cytoplasm<ref name='S000075481'>Gelling CL, et al. (2004) Identification of a novel one-carbon metabolism regulon in Saccharomyces cerevisiae. J Biol Chem 279(8):7072-81 {{SGDpaper|S000075481}} PMID 14645232</ref><ref name='S000056431'>Piper MD, et al. (2000) Regulation of the balance of one-carbon metabolism in Saccharomyces cerevisiae. J Biol Chem 275(40):30987-95 {{SGDpaper|S000056431}} PMID 10871621</ref><ref name='S000047381'>Sinclair DA, et al. (1996) Specific induction by glycine of the gene for the P-subunit of glycine decarboxylase from Saccharomyces cerevisiae. Mol Microbiol 19(3):611-23
 
  {{SGDpaper|S000047381}} PMID 8830251</ref>
 
  {{SGDpaper|S000047381}} PMID 8830251</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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=== Protein Details ===
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[[Category:Topic:Protein Details]]
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==== Protein Localization ====
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Protein identified in a purified mitochondrial extract. <ref name='S000074509'>Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 {{SGDpaper|S000074509}} PMID 14597615</ref> <ref name = 'CAset9949-2004-04-08'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=9949 Steffen Ohlmeier] on 2004-04-08</ref>
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YMR189W
Gene name GCV2
Aliases GSD2
Feature type ORF, Verified
Coordinates Chr XIII:637500..640604
Primary SGDID S000004801


Description of YMR189W: P subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF; expression is regulated by levels of 5,10-methylene-THF in the cytoplasm[1][2][3]




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Community Commentary

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Protein Details

Protein Localization

Protein identified in a purified mitochondrial extract. [4] [5]





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References

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  1. Gelling CL, et al. (2004) Identification of a novel one-carbon metabolism regulon in Saccharomyces cerevisiae. J Biol Chem 279(8):7072-81 SGD PMID 14645232
  2. Piper MD, et al. (2000) Regulation of the balance of one-carbon metabolism in Saccharomyces cerevisiae. J Biol Chem 275(40):30987-95 SGD PMID 10871621
  3. Sinclair DA, et al. (1996) Specific induction by glycine of the gene for the P-subunit of glycine decarboxylase from Saccharomyces cerevisiae. Mol Microbiol 19(3):611-23 SGD PMID 8830251
  4. Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 SGD PMID 14597615
  5. submitted by Steffen Ohlmeier on 2004-04-08

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