YMR135C

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Systematic name YMR135C
Gene name GID8
Aliases DCR1
Feature type ORF, Verified
Coordinates Chr XIII:540056..538689
Primary SGDID S000004742


Description of YMR135C: Protein of unknown function, involved in proteasome-dependent catabolite inactivation of fructose-1,6-bisphosphatase; contains LisH and CTLH domains, like Vid30p; dosage-dependent regulator of START[1][2]




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References

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  1. Pathak R, et al. (2004) Gid8p (Dcr1p) and Dcr2p function in a common pathway to promote START completion in Saccharomyces cerevisiae. Eukaryot Cell 3(6):1627-38 SGD PMID 15590836
  2. Regelmann J, et al. (2003) Catabolite degradation of fructose-1,6-bisphosphatase in the yeast Saccharomyces cerevisiae: a genome-wide screen identifies eight novel GID genes and indicates the existence of two degradation pathways. Mol Biol Cell 14(4):1652-63 SGD PMID 12686616

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