Difference between revisions of "YMR061W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004665 YMR061W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''RNA14 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''RNA14 '' | ||
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| − | '''Description of YMR061W:''' | + | '''Description of YMR061W:''' Component of the cleavage and polyadenylation factor I (CF I); CF 1, composed of the CF 1A complex (Rna14p, Rna15p, Clp1p, Pcf11p) and Hrp1, is involved in cleavage and polyadenylation of mRNA 3' ends; bridges interaction between Rna15p and Hrp1p in the CF I complex; mutant displays reduced transcription elongation in the G-less-based run-on (GLRO) assay; required for gene looping<ref name='S000147218'>Gordon J, et al. (2011) Reconstitution of CF IA form overexpressed subunits reveals stoichiometry and provides insight into molecular topology. Biochemistry () {{SGDpaper|S000147218}} PMID 22026644</ref><ref name='S000060315'>Gross S and Moore C (2001) Five subunits are required for reconstitution of the cleavage and polyadenylation activities of Saccharomyces cerevisiae cleavage factor I. Proc Natl Acad Sci U S A 98(11):6080-5 {{SGDpaper|S000060315}} PMID 11344258</ref><ref name='S000068788'>Gross S and Moore CL (2001) Rna15 interaction with the A-rich yeast polyadenylation signal is an essential step in mRNA 3'-end formation. Mol Cell Biol 21(23):8045-55 {{SGDpaper|S000068788}} PMID 11689695</ref><ref name='S000146442'>Medler S, et al. (2011) Evidence for a complex of TFIIB with poly(A) polymerase and cleavage factor 1 subunits required for gene looping. J Biol Chem () {{SGDpaper|S000146442}} PMID 21835917</ref><ref name='S000146226'>Tous C, et al. (2011) A novel assay identifies transcript elongation roles for the Nup84 complex and RNA processing factors. EMBO J 30(10):1953-64 |
{{SGDpaper|S000146226}} PMID 21478823</ref> | {{SGDpaper|S000146226}} PMID 21478823</ref> | ||
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Latest revision as of 07:45, 23 January 2012
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| Systematic name | YMR061W |
| Gene name | RNA14 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:392755..394788 |
| Primary SGDID | S000004665 |
Description of YMR061W: Component of the cleavage and polyadenylation factor I (CF I); CF 1, composed of the CF 1A complex (Rna14p, Rna15p, Clp1p, Pcf11p) and Hrp1, is involved in cleavage and polyadenylation of mRNA 3' ends; bridges interaction between Rna15p and Hrp1p in the CF I complex; mutant displays reduced transcription elongation in the G-less-based run-on (GLRO) assay; required for gene looping[1][2][3][4][5]
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References
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- ↑ Gordon J, et al. (2011) Reconstitution of CF IA form overexpressed subunits reveals stoichiometry and provides insight into molecular topology. Biochemistry () SGD PMID 22026644
- ↑ Gross S and Moore C (2001) Five subunits are required for reconstitution of the cleavage and polyadenylation activities of Saccharomyces cerevisiae cleavage factor I. Proc Natl Acad Sci U S A 98(11):6080-5 SGD PMID 11344258
- ↑ Gross S and Moore CL (2001) Rna15 interaction with the A-rich yeast polyadenylation signal is an essential step in mRNA 3'-end formation. Mol Cell Biol 21(23):8045-55 SGD PMID 11689695
- ↑ Medler S, et al. (2011) Evidence for a complex of TFIIB with poly(A) polymerase and cleavage factor 1 subunits required for gene looping. J Biol Chem () SGD PMID 21835917
- ↑ Tous C, et al. (2011) A novel assay identifies transcript elongation roles for the Nup84 complex and RNA processing factors. EMBO J 30(10):1953-64 SGD PMID 21478823
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