Difference between revisions of "YMR055C"
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| − | '''Description of YMR055C:''' Mitotic exit network regulator, forms GTPase-activating Bfa1p-Bub2p complex that binds Tem1p and spindle pole bodies, blocks cell cycle progression before anaphase in response to spindle and kinetochore damage<ref name=' | + | '''Description of YMR055C:''' Mitotic exit network regulator, forms GTPase-activating Bfa1p-Bub2p complex that binds Tem1p and spindle pole bodies, blocks cell cycle progression before anaphase in response to spindle and kinetochore damage<ref name='S000040583'>Fraschini R, et al. (1999) Budding yeast Bub2 is localized at spindle pole bodies and activates the mitotic checkpoint via a different pathway from Mad2. J Cell Biol 145(5):979-91 {{SGDpaper|S000040583}} PMID 10352016</ref><ref name='S000047472'>Pereira G, et al. (2000) The Bub2p spindle checkpoint links nuclear migration with mitotic exit. Mol Cell 6(1):1-10 {{SGDpaper|S000047472}} PMID 10949022</ref><ref name='S000059317'>Krishnan R, et al. (2000) Saccharomyces cerevisiae BUB2 prevents mitotic exit in response to both spindle and kinetochore damage. Genetics 156(2):489-500 {{SGDpaper|S000059317}} PMID 11014800</ref><ref name='S000076098'>Molk JN, et al. (2004) The differential roles of budding yeast Tem1p, Cdc15p, and Bub2p protein dynamics in mitotic exit. Mol Biol Cell 15(4):1519-32 {{SGDpaper|S000076098}} PMID 14718561</ref><ref name='S000068993'>Hu F, et al. (2001) Regulation of the Bub2/Bfa1 GAP complex by Cdc5 and cell cycle checkpoints. Cell 107(5):655-65 {{SGDpaper|S000068993}} PMID 11733064</ref><ref name='S000074671'>Pereira G, et al. (2001) Modes of spindle pole body inheritance and segregation of the Bfa1p-Bub2p checkpoint protein complex. EMBO J 20(22):6359-70 {{SGDpaper|S000074671}} PMID 11707407</ref><ref name='S000074906'>Pereira G, et al. (2002) Regulation of the Bfa1p-Bub2p complex at spindle pole bodies by the cell cycle phosphatase Cdc14p. J Cell Biol 157(3):367-79 |
| − | {{SGDpaper| | + | {{SGDpaper|S000074906}} PMID 11970961</ref> |
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Revision as of 14:05, 31 March 2009
Share your knowledge...Edit this entry! <protect>
| Systematic name | YMR055C |
| Gene name | BUB2 |
| Aliases | PAC7 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:387020..386100 |
| Primary SGDID | S000004659 |
Description of YMR055C: Mitotic exit network regulator, forms GTPase-activating Bfa1p-Bub2p complex that binds Tem1p and spindle pole bodies, blocks cell cycle progression before anaphase in response to spindle and kinetochore damage[1][2][3][4][5][6][7]
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References
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- ↑ Fraschini R, et al. (1999) Budding yeast Bub2 is localized at spindle pole bodies and activates the mitotic checkpoint via a different pathway from Mad2. J Cell Biol 145(5):979-91 SGD PMID 10352016
- ↑ Pereira G, et al. (2000) The Bub2p spindle checkpoint links nuclear migration with mitotic exit. Mol Cell 6(1):1-10 SGD PMID 10949022
- ↑ Krishnan R, et al. (2000) Saccharomyces cerevisiae BUB2 prevents mitotic exit in response to both spindle and kinetochore damage. Genetics 156(2):489-500 SGD PMID 11014800
- ↑ Molk JN, et al. (2004) The differential roles of budding yeast Tem1p, Cdc15p, and Bub2p protein dynamics in mitotic exit. Mol Biol Cell 15(4):1519-32 SGD PMID 14718561
- ↑ Hu F, et al. (2001) Regulation of the Bub2/Bfa1 GAP complex by Cdc5 and cell cycle checkpoints. Cell 107(5):655-65 SGD PMID 11733064
- ↑ Pereira G, et al. (2001) Modes of spindle pole body inheritance and segregation of the Bfa1p-Bub2p checkpoint protein complex. EMBO J 20(22):6359-70 SGD PMID 11707407
- ↑ Pereira G, et al. (2002) Regulation of the Bfa1p-Bub2p complex at spindle pole bodies by the cell cycle phosphatase Cdc14p. J Cell Biol 157(3):367-79 SGD PMID 11970961
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