YML121W

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Systematic name YML121W
Gene name GTR1
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:26930..27862


Description of YML121W: Cytoplasmic GTP binding protein and negative regulator, with homolog Gtr2p, of the Ran/Tc4 GTPase cycle; component of GSE complex, which is required for sorting of Gap1p; involved in phosphate transport; has homology to human RagA and RagB[1][2][3][4][5][6]




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References

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  1. Gao M and Kaiser CA (2006) A conserved GTPase-containing complex is required for intracellular sorting of the general amino-acid permease in yeast. Nat Cell Biol 8(7):657-67 SGD PMID 16732272
  2. Palecek SP, et al. (2000) Genetic analysis reveals that FLO11 upregulation and cell polarization independently regulate invasive growth in Saccharomyces cerevisiae. Genetics 156(3):1005-23 SGD PMID 11063681
  3. Hirose E, et al. (1998) RagA is a functional homologue of S. cerevisiae Gtr1p involved in the Ran/Gsp1-GTPase pathway. J Cell Sci 111 ( Pt 1)():11-21 SGD PMID 9394008
  4. Nakashima N, et al. (1999) Saccharomyces cerevisiae putative G protein, Gtr1p, which forms complexes with itself and a novel protein designated as Gtr2p, negatively regulates the Ran/Gsp1p G protein cycle through Gtr2p. Genetics 152(3):853-67 SGD PMID 10388807
  5. Bun-Ya M, et al. (1992) Putative GTP-binding protein, Gtr1, associated with the function of the Pho84 inorganic phosphate transporter in Saccharomyces cerevisiae. Mol Cell Biol 12(7):2958-66 SGD PMID 1620108
  6. Nakashima N, et al. (1996) Putative GTPase Gtr1p genetically interacts with the RanGTPase cycle in Saccharomyces cerevisiae. J Cell Sci 109 ( Pt 9)():2311-8 SGD PMID 8886981

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