Difference between revisions of "YML062C"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 13:02, 21 February 2007

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Systematic name YML062C
Gene name MFT1
Aliases MFT52
Feature type ORF, Verified
Coordinates Chr XIII:148683..147505


Description of YML062C: Subunit of the THO complex, which is a nuclear complex comprised of Hpr1p, Mft1p, Rlr1p, and Thp2p, that is involved in transcription elongation and mitotic recombination; involved in telomere maintenance[1][2][3][4]




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References

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  1. Askree SH, et al. (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63 SGD PMID 15161972
  2. Jimeno S, et al. (2002) The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability. EMBO J 21(13):3526-35 SGD PMID 12093753
  3. Strasser K, et al. (2002) TREX is a conserved complex coupling transcription with messenger RNA export. Nature 417(6886):304-8 SGD PMID 11979277
  4. Chavez S, et al. (2000) A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae. EMBO J 19(21):5824-34 SGD PMID 11060033

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